NSTL国家科技图书文献中心

1. Prostate-specific membrane antigen as target for vasculature-directed therapeutic strategies in solid tumors NSTL国家科技图书文献中心

Puik J.R. | Le C.... - 《Critical reviews in oncology/hematology》 - 2025,205 - 104556～104556 - 共13页 - 被引量：1

摘要：© 2024 The AuthorsProstate-specific membrane | antigen (PSMA) is one of the few biomarkers which has | theranostic biomarker for patients with prostate* cancer. In* | the context of prostate* cancer, PSMA is* | overexpressed on the cell membrane* of tumor cells, making it a*

关键词： angiogenesis | immunotherapy | prostate cancer | Prostate-Specific Membrane Antigen | tumor vasculature | vaccination

2. The Safety and Efficacy of Targeted Alpha Therapy, Ac-225 Prostate-Specific Membrane Antigen, in Patients With Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-Analysis NSTL国家科技图书文献中心

Besiroglu, Huseyin | Kadihasanoglu, Musta... - 《The Prostate》 - 2025,85(6) - 541～557 - 共17页

摘要：. Actinium 225 (225Ac) prostate-specific membrane antigen | prostate cancer (mCRPC) is a challenging disease with a | BackgroundMetastatic castration resistance | significant burden of mortality and morbidity. Most of the | patients attain resistance to the available treatments

关键词： Actinium-225 | meta-analysis | metastatic castration resistance prostate cancer | prostate cancer | prostate-specific membrane antigen-targeted therapy | targeted alpha therapy

3. Novel astatine ( 211 At)-labelled prostate-specific membrane antigen ligand with a neopentyl-glycol structure: evaluation of stability, efficacy, and safety using a prostate cancer xenograft model NSTL国家科技图书文献中心

Yaginuma, Kei | Takahashi, Kazuhiro ... - 《European Journal of Nuclear Medicine and Molecular Imaging》 - 2025,52(2) - 469～481 - 共13页

摘要：Purpose Prostate-specific membrane antigen | -resistant prostate* cancer (mCRPC). Though astatine-211 (At* | (PSMA)-targeted alpha therapy is considered a | promising alternative treatment for metastatic castration | -211) is potentially useful alpha-emitter producible

关键词： Prostate-specific membrane antigen | Astatine-211 | Neopentyl glycol structure | Metastatic castration-resistant prostate cancer | Targeted alpha therapy | Preclinical evaluation

4. Synthesis and Preclinical Evaluation of Dual-Specific Probe Targeting Glypican-3 and Prostate-Specific Membrane Antigen for Hepatocellular Carcinoma PET Imaging NSTL国家科技图书文献中心

Chen, Lixing | Cheng, Siyuan ... - 《Molecular pharmaceutics》 - 2025,22(1) - 209～220 - 共12页

摘要： (GPC3) and prostate-specific* membrane antigen (PSMA* | ). Hereby, a dual-specific* probe targeting Glypican-3* | Positron emission tomography (PET) is a | promising modality for early diagnosis, accurate detection | , and staging of hepatocellular carcinoma (HCC

关键词： hepatocellular carcinoma | heterodimer | Glypican-3 | prostate-specific membrane antigen | positron emissiontomography

5. Novel Application of Lutetium-177-Prostate Specific Membrane Antigen (LuPSMA) Radioligand Therapy for Metastatic Synovial Sarcoma NSTL国家科技图书文献中心

Mcbean, Rhiannon S. | Tatkovic, Annaleis M...... - 《Journal of medical imaging and radiation oncology》 - 2025,69(3) - 381～385 - 共5页

摘要：. Given prostate* specific membrane antigen (PSMA* | prostate cancer, for patients with other PSMA-expressing | Intracranial synovial sarcoma is exceedingly | rare, with only 24 cases reported in the literature | ) expression is found in the neovascular endothelium of solid

关键词： LuPSMA | Lutetium-177 | radioligand therapy | synovial sarcoma | theranostics | Lutetium‐177

6. Novel Radiotheranostic Ligands Targeting Prostate-Specific Membrane Antigen Based on Dual Linker Approach NSTL国家科技图书文献中心

Kazuta, Nobuki | Nakashima, Kazuma ... - 《Molecular pharmaceutics》 - 2025,22(1) - 377～386 - 共10页

摘要：Radiotheranostics using prostate-specific | membrane antigen (PSMA)-targeting radioligands offers | precision medicine by performing radionuclide therapy | based on results of diagnosis. Albumin binder (ALB | ) binds to albumin reversibly and contributes to

关键词： radiotheranostics | prostate-specificmembrane antigen | albumin binder | d -glutamic acid | 4-(aminomethyl)benzoicacid | dual functional linkers

7. Design, synthesis, and biological evaluation of novel thiourea derivatives as small molecule inhibitors for prostate specific membrane antigen NSTL国家科技图书文献中心

Sengupta, Sagnik | Pandit, Amit ... - 《Bioorganic chemistry》 - 2025,155 - 共18页

摘要： biomarker, prostate* specific membrane antigen (PSMA* | Prostate cancer (PCa) has emerged to be the | , these PSMA-specific* small molecule radio-imaging* | second leading cause of cancer-related deaths in men | . Molecular imaging of PCa using targeted

关键词： Prostate cancer | Targeting ligands | Drug-delivery | Radioisotopes | PSMA

8. CXCR2 expression is associated with prostate-specific membrane antigen expression in hepatocellular carcinoma: reappraisal of tumor microenvironment and angiogenesis NSTL国家科技图书文献中心

Park, Eundong | Subasi, Nusret Bekir ... - 《Clinical & translational oncology》 - 2025,27(6) - 2544～2556 - 共13页

摘要：. Prostate-specific* membrane antigen (PSMA) is expressed in* | PurposeAngiogenesis is a critical component of | neoplastic progression, and inflammatory cells within the | tumor microenvironment contribute to neoangiogenesis | the neovasculature of various solid tumors

关键词： CXCR2 | PSMA | Hepatocellular carcinoma | Neutrophil | Angiogenesis

9. Genetically modified extracellular vesicles loaded with activated gasdermin D potentially inhibit prostate-specific membrane antigen-positive prostate carcinoma growth and enhance immunotherapy NSTL国家科技图书文献中心

Gao, Ke | Xi, Wenjin ... - 《Biomaterials》 - 2025,315 - 共17页

摘要：) with high affinity for prostate-specific membrane | Prostate cancer (PCa) is associated with poor | antigen (PSMA) on their surfaces and is loaded with the | immunogenicity and lymphocytic infiltration, and immunotherapy | effective against PCa remains unavailable. Pyroptosis, a

关键词： Prostate cancer | Extracellular vesicles | Drug delivery | Immunotherapy | Gasdermin D

10. Prediction of Lesion-Based Treatment Response after Two Cycles of Lu-177 Prostate Specific Membrane Antigen Treatment in Metastatic Castration-Resistant Prostate Cancer Using Machine Learning NSTL国家科技图书文献中心

Bulbul, Ogun | Nak, Demet ... - 《Urologia internationalis》 - 2025,109(2) - 128～134 - 共7页

摘要：-specific* membrane antigen (PSMA) therapy is a* | Introduction: Lutetium-177 (Lu-177) prostate | metastatic castration-resistant prostate* cancer (MCRPC). We* | radionuclide treatment that prolongs overall survival in | aimed to predict lesion-based treatment response after

摘要：© 2024 The AuthorsProstate-specific membrane | antigen (PSMA) is one of the few biomarkers which has | theranostic biomarker for patients with prostate* cancer. In* | the context of prostate* cancer, PSMA is* | overexpressed on the cell membrane* of tumor cells, making it a*

关键词： angiogenesis | immunotherapy | prostate cancer | Prostate-Specific Membrane Antigen | tumor vasculature | vaccination

摘要：. Actinium 225 (225Ac) prostate-specific membrane antigen | prostate cancer (mCRPC) is a challenging disease with a | BackgroundMetastatic castration resistance | significant burden of mortality and morbidity. Most of the | patients attain resistance to the available treatments

关键词： Actinium-225 | meta-analysis | metastatic castration resistance prostate cancer | prostate cancer | prostate-specific membrane antigen-targeted therapy | targeted alpha therapy

摘要：Purpose Prostate-specific membrane antigen | -resistant prostate* cancer (mCRPC). Though astatine-211 (At* | (PSMA)-targeted alpha therapy is considered a | promising alternative treatment for metastatic castration | -211) is potentially useful alpha-emitter producible

关键词： Prostate-specific membrane antigen | Astatine-211 | Neopentyl glycol structure | Metastatic castration-resistant prostate cancer | Targeted alpha therapy | Preclinical evaluation

摘要： (GPC3) and prostate-specific* membrane antigen (PSMA* | ). Hereby, a dual-specific* probe targeting Glypican-3* | Positron emission tomography (PET) is a | promising modality for early diagnosis, accurate detection | , and staging of hepatocellular carcinoma (HCC

关键词： hepatocellular carcinoma | heterodimer | Glypican-3 | prostate-specific membrane antigen | positron emissiontomography

摘要：. Given prostate* specific membrane antigen (PSMA* | prostate cancer, for patients with other PSMA-expressing | Intracranial synovial sarcoma is exceedingly | rare, with only 24 cases reported in the literature | ) expression is found in the neovascular endothelium of solid

关键词： LuPSMA | Lutetium-177 | radioligand therapy | synovial sarcoma | theranostics | Lutetium‐177

摘要：Radiotheranostics using prostate-specific | membrane antigen (PSMA)-targeting radioligands offers | precision medicine by performing radionuclide therapy | based on results of diagnosis. Albumin binder (ALB | ) binds to albumin reversibly and contributes to

关键词： radiotheranostics | prostate-specificmembrane antigen | albumin binder | d -glutamic acid | 4-(aminomethyl)benzoicacid | dual functional linkers

摘要： biomarker, prostate* specific membrane antigen (PSMA* | Prostate cancer (PCa) has emerged to be the | , these PSMA-specific* small molecule radio-imaging* | second leading cause of cancer-related deaths in men | . Molecular imaging of PCa using targeted

关键词： Prostate cancer | Targeting ligands | Drug-delivery | Radioisotopes | PSMA

摘要：. Prostate-specific* membrane antigen (PSMA) is expressed in* | PurposeAngiogenesis is a critical component of | neoplastic progression, and inflammatory cells within the | tumor microenvironment contribute to neoangiogenesis | the neovasculature of various solid tumors

关键词： CXCR2 | PSMA | Hepatocellular carcinoma | Neutrophil | Angiogenesis

摘要：) with high affinity for prostate-specific membrane | Prostate cancer (PCa) is associated with poor | antigen (PSMA) on their surfaces and is loaded with the | immunogenicity and lymphocytic infiltration, and immunotherapy | effective against PCa remains unavailable. Pyroptosis, a

关键词： Prostate cancer | Extracellular vesicles | Drug delivery | Immunotherapy | Gasdermin D

摘要：-specific* membrane antigen (PSMA) therapy is a* | Introduction: Lutetium-177 (Lu-177) prostate | metastatic castration-resistant prostate* cancer (MCRPC). We* | radionuclide treatment that prolongs overall survival in | aimed to predict lesion-based treatment response after

关键词： Texture analysis | Machine learning | Ga-68 PSMA positron emission tomography/computed tomography | Lutetium-177 PSMA | Prediction

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：© 2024 The AuthorsProstate-specific membrane | antigen (PSMA) is one of the few biomarkers which has | theranostic biomarker for patients with prostate cancer. In | the context of prostate cancer, PSMA is | overexpressed on the cell membrane of tumor cells, making it a

关键词： angiogenesis | immunotherapy | prostate cancer | Prostate-Specific Membrane Antigen | tumor vasculature | vaccination

摘要：. Actinium 225 (225Ac) prostate-specific membrane antigen | prostate cancer (mCRPC) is a challenging disease with a | BackgroundMetastatic castration resistance | significant burden of mortality and morbidity. Most of the | patients attain resistance to the available treatments

关键词： Actinium-225 | meta-analysis | metastatic castration resistance prostate cancer | prostate cancer | prostate-specific membrane antigen-targeted therapy | targeted alpha therapy

摘要：Purpose Prostate-specific membrane antigen | -resistant prostate cancer (mCRPC). Though astatine-211 (At | (PSMA)-targeted alpha therapy is considered a | promising alternative treatment for metastatic castration | -211) is potentially useful alpha-emitter producible

关键词： Prostate-specific membrane antigen | Astatine-211 | Neopentyl glycol structure | Metastatic castration-resistant prostate cancer | Targeted alpha therapy | Preclinical evaluation

摘要： (GPC3) and prostate-specific membrane antigen (PSMA | ). Hereby, a dual-specific probe targeting Glypican-3 | Positron emission tomography (PET) is a | promising modality for early diagnosis, accurate detection | , and staging of hepatocellular carcinoma (HCC

关键词： hepatocellular carcinoma | heterodimer | Glypican-3 | prostate-specific membrane antigen | positron emissiontomography

摘要：. Given prostate specific membrane antigen (PSMA | prostate cancer, for patients with other PSMA-expressing | Intracranial synovial sarcoma is exceedingly | rare, with only 24 cases reported in the literature | ) expression is found in the neovascular endothelium of solid

关键词： LuPSMA | Lutetium-177 | radioligand therapy | synovial sarcoma | theranostics | Lutetium‐177

摘要：Radiotheranostics using prostate-specific | membrane antigen (PSMA)-targeting radioligands offers | precision medicine by performing radionuclide therapy | based on results of diagnosis. Albumin binder (ALB | ) binds to albumin reversibly and contributes to

关键词： radiotheranostics | prostate-specificmembrane antigen | albumin binder | d -glutamic acid | 4-(aminomethyl)benzoicacid | dual functional linkers

摘要： biomarker, prostate specific membrane antigen (PSMA | Prostate cancer (PCa) has emerged to be the | , these PSMA-specific small molecule radio-imaging | second leading cause of cancer-related deaths in men | . Molecular imaging of PCa using targeted

关键词： Prostate cancer | Targeting ligands | Drug-delivery | Radioisotopes | PSMA

摘要：. Prostate-specific membrane antigen (PSMA) is expressed in | PurposeAngiogenesis is a critical component of | neoplastic progression, and inflammatory cells within the | tumor microenvironment contribute to neoangiogenesis | the neovasculature of various solid tumors

关键词： CXCR2 | PSMA | Hepatocellular carcinoma | Neutrophil | Angiogenesis

摘要：) with high affinity for prostate-specific membrane | Prostate cancer (PCa) is associated with poor | antigen (PSMA) on their surfaces and is loaded with the | immunogenicity and lymphocytic infiltration, and immunotherapy | effective against PCa remains unavailable. Pyroptosis, a

关键词： Prostate cancer | Extracellular vesicles | Drug delivery | Immunotherapy | Gasdermin D

摘要：-specific membrane antigen (PSMA) therapy is a | Introduction: Lutetium-177 (Lu-177) prostate | metastatic castration-resistant prostate cancer (MCRPC). We | radionuclide treatment that prolongs overall survival in | aimed to predict lesion-based treatment response after

关键词： Texture analysis | Machine learning | Ga-68 PSMA positron emission tomography/computed tomography | Lutetium-177 PSMA | Prediction

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：© 2024 The AuthorsProstate-specific membrane | antigen (PSMA) is one of the few biomarkers which has | theranostic biomarker for patients with prostate* cancer. In* | the context of prostate* cancer, PSMA is* | overexpressed on the cell membrane* of tumor cells, making it a*

摘要：Purpose Prostate-specific membrane antigen | -resistant prostate* cancer (mCRPC). Though astatine-211 (At* | (PSMA)-targeted alpha therapy is considered a | promising alternative treatment for metastatic castration | -211) is potentially useful alpha-emitter producible

摘要： (GPC3) and prostate-specific* membrane antigen (PSMA* | ). Hereby, a dual-specific* probe targeting Glypican-3* | Positron emission tomography (PET) is a | promising modality for early diagnosis, accurate detection | , and staging of hepatocellular carcinoma (HCC

摘要：. Given prostate* specific membrane antigen (PSMA* | prostate cancer, for patients with other PSMA-expressing | Intracranial synovial sarcoma is exceedingly | rare, with only 24 cases reported in the literature | ) expression is found in the neovascular endothelium of solid

摘要： biomarker, prostate* specific membrane antigen (PSMA* | Prostate cancer (PCa) has emerged to be the | , these PSMA-specific* small molecule radio-imaging* | second leading cause of cancer-related deaths in men | . Molecular imaging of PCa using targeted

摘要：. Prostate-specific* membrane antigen (PSMA) is expressed in* | PurposeAngiogenesis is a critical component of | neoplastic progression, and inflammatory cells within the | tumor microenvironment contribute to neoangiogenesis | the neovasculature of various solid tumors

摘要：-specific* membrane antigen (PSMA) therapy is a* | Introduction: Lutetium-177 (Lu-177) prostate | metastatic castration-resistant prostate* cancer (MCRPC). We* | radionuclide treatment that prolongs overall survival in | aimed to predict lesion-based treatment response after